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The 10th annual Inclusion in Science, Learning a New Direction Conference on Disability (ISLAND) was hosted by the University of Alabama in Huntsville (UAH), with support from the UAH College of Education, UAH Office of Academic Affairs, and the Alabama Institute for the Deaf and Blind, as well as the Princeton Center for Complex Materials (PCCM), a National Science Foundation funded Materials Research Science and Engineering Center (MRSEC) and the UAH Center for Cybersecurity Research and Education (CCRE). On October 4-5, 2019, the conference was held at the U.S. Space and Rocket Center facility and at the new Student Services Building on the UAH campus. This year’s presentations included innovative research by science educators in formal and informal educational settings, from pre-K-12 to higher education, as well as from science education researchers, access technology developers, and other persons interested in the promotion of the full inclusion of people with disabilities in Science, Technology, Engineering, and Mathematics (STEM) professions. The 2019 ISLAND conference featured seventeen presentations over the two-day period. The following is intended to give the reader an overview of these presentations. This is not intended to be a comprehensive synopsis of all aspects of the discussions that were presented. Rather, readers are encouraged to review full papers authored by the presenters highlighted herein. All presenters were invited to contribute papers to this special section of JSESD.