Abstract

Objectives:

This paper reviews the evidence relating to the clinical screening of PCOS in adolescents and alternative management.

Methods:

Using Web of Science, phrases such as “PCOS Screening”, “Adolescents”, “Alternative Therapy”, and “PCOS Overview” were searched. Only articles published between 2000 - 2023 were allowed in this literature review resulting in 25 articles being utilized.

Results:

Studies using 2D ultrasonography revealed adolescents with PCOS had a mean ovarian volume of 9.29 +/- 4.62 milliliters, while the control group had a volume of 4.77+/- 2.30 milliliters (p < 0.001)

A prospective correlation study found that PCOS adolescents had an elevated mean LH level of 7.75 + 4.6 m IU/ml, while the control group had an LH level of 5.06 + 1.55 m IU/ml (p < 0.01)2 .

A randomized, double–blind study found that PCOS patients who took the inositols, MYO or DIC, experienced a decrease in their total cholesterol (p < 0.05), triglycerides (p < 0.05), and basal insulin serum levels (p < 0.05)

A 252-participant study showed that laparoscopic ovarian electrocautery resulted in 92% ovulation success, and 84% of the participants became pregnant.25

Conclusion:

Adolescents with PCOS have an enlarged ovarian volume and a statistically elevated LH.2 As such, these elements are appropriate criteria to diagnose PCOS in adolescents.

The mechanism of action behind inositol and its impact on PCOS is plausible but requires further randomized control trials Laparoscopic ovarian diathermy is effective at restoring ovulation and promoting pregnancy, but it should be reserved as a last-line therapy.

Publication Date

1-1-2024

Document Type

Master's Project

Student Type

Graduate

Degree Name

Physician Assistant (MS)

Department, Program, or Center

Physician Assistant

College

College of Health Sciences and Technology

Advisor

Janice Shirley

Campus

RIT – Main Campus

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