The Instrumentation Laboratory's MicroCentrifugal Analyzer (MCA) was evaluated for precision, linearity and accuracy for albumin, alanine transaminase (ALT), aspartate transaminase (AST) , alkaline phosphatase, creatine kinase (CK), cerebrospinal fluid (CSF) total protein, cholesterol, glucose, gamma-glutamyl transpeptidase (GGT), lactic dehydrogenase (LDH) , phosphorous, total protein, and triglyceride. Within-run, within-day, day-to-day, and total precision was comparable to or exceeded manufacturer's claims and was comparable to the precision in existing in-house tests. A comparison of methods for the MicroCentrifugal Analyzer with those used on the Technicon SMA 12/60, the Abbott ABA-100 and the Kodak Ektachem 400 showed very good correlation with minimal random error - As a result of this study, the MicroCentrifugal Analyzer was implemented in this laboratory as a replacement instrument for the ABA 100 and as a backup instrument for the SMA 12/60 and Ektachem 400. A new activated creatine kinase kit was adopted and the existing cerebrospinal fluid total protein biuret method was replaced with an automated Coomassie blue method.

Library of Congress Subject Headings

Centrifuges--Evaluation; Clinical chemistry--Instruments--Evaluation

Publication Date


Document Type


Department, Program, or Center

Thomas H. Gosnell School of Life Sciences (COS)


Bayer, R.

Advisor/Committee Member

Ehpenine, Joseph

Advisor/Committee Member

Anmer, James


Note: imported from RIT’s Digital Media Library running on DSpace to RIT Scholar Works. Physical copy available through RIT's The Wallace Library at: QP519.9.C44 M353 1988


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