The degradation of DNA in forensic genetic genealogy can hinder timely results in victim or perpetrator identification. Identification of an unidentified victim, a “Doe”, involves analyzing the degraded DNA against reference genomes. Organizations like the DNA Doe Project and Identifinders currently manually compares the genomes in a spreadsheet with data input slowing down the investigative process. I propose a program to automate the data input and comparison to increase the speed at which Identifinders can continue their research into identifying victims. Comparative DNA Degradation Automation (CDDA) automates the process of creating a simulated degraded DNA profile in less than a second on average. This program could be used not only by organizations like Identifinders and the DNA Doe Project, but also used in future research where natural DNA decomposition is not possible.
Library of Congress Subject Headings
Genetic genealogy; DNA--Testing
Department, Program, or Center
Thomas H. Gosnell School of Life Sciences (COS)
Gary R. Skuse
Pfaff, Jennifer, "Comparative DNA Degradation Automation for Identifinders" (2021). Thesis. Rochester Institute of Technology. Accessed from
RIT – Main Campus